ISSN 2398-2977      

Pheochromocytoma

pequis

Introduction

  • A pheochromocytoma is the most frequently diagnosed adrenomedullary neoplasm of equids although the disorder itself is extremely rare.
  • Cause: neoplasm of chromaffin cells or tissue.
  • Signs: profuse sweating, edema, cardiac problems, colic. May be asymptomatic.
  • Treatment: adrenalectomy
  • Prognosis: good to guarded.

Pathogenesis

Etiology

  • Neoplasm of chromaffin cells of either the left or the right adrenal gland.
  • Both adrenal glands may be involved.

Pathophysiology

  • The exact cause of the neoplasm is unknown.
  • The clinical signs are largely attributable to the increased production and release of catecholamines.

Timecourse

  • Unknown.
  • Some cases are asymptomatic.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Johnson P J, Goetz T E, Foreman J H & Zachary J F (1995) Pheochromocytoma in two horses. JAVMA 206, 837-841 PubMed.
  • Yovich J V, Horney F D & Hardee G E (1984) Pheochromocytoma in the horse and measurement of norepinephrine levels in horses. Can Vet J 25, 21-25 PubMed.
  • Yovich J V & Ducharme N G (1983) Ruptured pheochromocytoma in a mare with colic. JAVMA 183, 462-464 PubMed.

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