ISSN 2398-2977      

Intestine: enteritis - idiopathic focal eosinophilic

pequis

Synonym(s): Multifocal eosinophilic enteritis, idiopathic eosinophilic enteritis, IFEE


Introduction

  • Cause: unknown.
  • Signs: small intestinal obstruction (non-strangulating).
  • Diagnosis: histology of intestinal biopsy.
  • Treatment: surgical resection.
  • Prognosis: good following resection.
  • Rare.

Pathogenesis

Etiology

  • Unknown.
  • Rule out parasites or fungi as a cause.
  • Possibly related to diet.

Pathophysiology

  • Obstruction of ingesta at site of lesion due to reduction in diameter of the bowel lumen at the site and possibly reduction in bowel wall motility at the affected site.
  • Distension of proximal small intestine.
  • Pain due to small intestinal distension progressing to gastric distension (and possible gastric rupture) if sequestered fluid is not removed by nasogastric intubation.

Timecourse

  • Unknown: may be a chronic lesion that reaches a critical mass or an acute inflammatory response.
  • Colic may have been evident for 4-12 h.

Epidemiology

  • Only 8 cases reported in literature.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Makinen P E, Archer D C, Baptiste K E et al (2008) Characterisation of the inflammatory reaction in equine idiopathic focal eosinophilic enteritis and diffuse eosinophilic enteritis. Equine Vet J 40 (4), 386-392 PubMed.
  • Proudman C J & Kipar A (2006) IFEE: new acronym, new challenge. Equine Vet J 38 (4), 290-291 PubMed.
  • Swain J M, Licka T, Rhind S M & Hudson N P H (2003) Multifocal eosinophilic enteritis associated with a small intestinal obstruction in a standardbred horse. Vet Rec 152, 648-651 PubMed.
  • Stanar L S, Little D, Redding W R & Jones S L (2002) Idiopathic eosinophilic enteritis in a 10 week old colt. Comp Cont Ed Pract Vet 24 (4), 342-347 VetMedResource.
  • Southwood L L, Kawcak C E,  Trotter G W, Stashak T S & Frisbe D D (2000) Idiopathic focal eosinophilic enteritis associated with small intestinal obstruction in 6 horses. Vet Surg 29 (5), 415-419 PubMed.

Other sources of information

  • Archer D C, Edwards G B, Kelly D F & Proudman C J (2004) Small Intestinal Obstruction Associated with Idiopathic Focal Eosinophilic Enteritis: 12 cases. In: Proc 43rd BEVA Congress. Equine Vet J Ltd, UK. pp 192.
  • Epidemiology of Colic Project, funded by the Horserace Betting Levy Board. Contact Debbie Archer BVMS CertES MRCVS, Department of Veterinary Clinical Sciences, The University of Liverpool, Liverpool L69 3BX, UK. Tel: +44 (0)151 795 6011; Fax: +44 (0)151 794 6048; Email: darcher@liverpool.ac.uk; Website: pcwww.liv.ac.uk/eeandefeproject.

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