ISSN 2398-2977      

Eyelid: neoplasia

pequis
Contributor(s):

Synonym(s): Eyelid cancer


Introduction

  • A new and abnormal growth on the eyelid, specifically one in which cell multiplication is uncontrolled and progressive (benign or malignant).
  • Melanoma, sarcoid, mast cell tumor, lymphoma, squamous cell carcinoma, myxoma.
  • Cause: various causes for the different types of tumor, eg exposure to high intensity sunlight in SCC.
  • Signs: masses on eyelids, ocular discharge, photophobia.
  • Diagnosis: biopsy.
  • Treatment: cryosurgery, surgical excision, topical corticosteroids, radiation.
  • Prognosis: good if treated properly. Some treatments can cause serious scarring and distortion with secondary effects.

Pathogenesis

Etiology

  • Squamous cell carcinoma is possibly actinic in origin (UV light related).
  • Sarcoids are highly associated with the presence of bovine papillomavirus (types 1 and 2).

Predisposing factors

General

  • Sarcoids at other sites predisposes to periocular sarcoid Sarcoid.
  • Lack of eyelid pigment (a strong but not certain predisposing factor) particularly along the mucocutaneous borders and third eyelid margin are very vulnerable to the development of squamous cell carcinoma.
  • Gray color strongly predisposes to the development of melanoma Eye: neoplasia - melanoma.

Timecourse

  • Usually slow.
  • Both sarcoid and squamous cell carcinoma may take around 2-12 months to develop significantly.
  • Melanomas are usually slow growing.
  • Timecourse is unpredictable.
  • Mast cell tumors Skin: neoplasia - mast cell tumor are slow growing.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Prevention

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Henson F M D & Dobson J M (2004) Use of radiation therapy in the treatment of equine neoplasia. Equine Vet Educ 16 (6), 315-318 Wiley.
  • Knottenbelt D C & Kelly D F (2000) The diagnosis and treatment of periorbital sarcoid in the horse: 445 cases from 1974 to 1999. Vet Ophthal. 3 (2), 169-191 PubMed.
  • Paterson S (1997) Treatment of superficial ulcerative squamous cell carcinoma in three horses with topical 5-fluorouracil. Vet Rec 141, 626-628 PubMed.
  • Hilbert B J, Farrell R K & Grant B D (1977) Cryotherapy of periocular squamous cell carcinoma in the horse. JAVMA 170, 1305-1308 PubMed.
  • Strafuss A C (1976) Squamous cell carcinoma in horses. JAVMA 168, 61-62 PubMed.

Other sources of information

  • Knottenbelt D C, Patterson-Kane J C & Snalune K L (2015) Clinical Equine Oncology. Elsevier Press.
  • Brooks D E (2002) Ophthalmology for the Equine Practitioner. Made Easy Series, Teton New Media, USA. pp 45-47.
  • Pascoe R R & Knottenbelt D C (1999) Chapter 19: Neoplastic Conditions. In: Manual of Equine Dermatology. W B Saunders. pp 244-252.
  • Theon A P (1997) Cisplatin Treatment for Cutaneous tumors. In: Current Therapy in Equine Medicine. 4th edn. Ed: Robinson N E. W B Saunders, USA. pp 372-377.
  • Barnett K C, Crispin S M, Lavach J D & Matthews A G (1995) Upper and Lower Eyelids. In: Colour Atlas and Text of Equine Ophthalmology. Mosby-Wolfe, UK. pp 58-64.
  • Pulley L T & Stannard A A (1990) Tumors of the Skin and Soft Tissues. In: Tumors in Domestic Animals. 3rd edn. Ed: Moulton J E. University of California Press, USA.
  • Lavach J D (1990) Chapter 3: Eyelids. In: Large Animal Ophthalmology. Mosby, USA. pp 4252.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code