ISSN 2398-2942      

Skin: impression smear

icanis

Introduction

  • Impression smears can be taken from any moist or greasy skin surface to see inflammatory, neoplastic or other cellular infiltrates, also to look for acantholytic keratinocytes, bacteria and yeasts.
  • They can also be taken from cut surface of a surgical specimen or post mortem specimen.

Uses

Advantages

  • Samples are easily and quickly taken and will allow immediate differentiation of neoplastic and infective disease in many cases.

Disadvantages

  • Surface bacteria may not be causative as lesions may be contaminated.  
  • Although most neoplastic lesions will exfoliate cells, some (eg sarcoma Soft tissue sarcoma) will not, so results may be erroneously negative.

Requirements

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Preparation

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Procedure

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Outcomes

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Miller W H, Griffin C E & Campbell (2013) Muller & Kirk's Small Animal Dermatology 7th edn. Elsevier Inc, Missouri, pp 81-86.
  • Villiers E & Blackwood L (2005) Canine and Feline Clinical Pathology. BSAVA 2nd edn. 

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