Canis ISSN: 2398-2942

Biopsy: skin

Synonym(s): Dermatology: biopsy skin

Introduction

  • Skin histopathology is a valuable aid to differential and definitive diagnosis of many skin disorders.

Uses

  • Definitive diagnosis of certain skin diseases.
  • Categorization of skin disease.
  • Exclusion of some diseases.

Advantages

  • Provides useful information.

Disadvantages

  • May not be diagnostic in all cases.
  • Sutures, dehiscence.
  • Most animals require sedation.
  • Nasal, facial and footpad lesions: may require short-acting general anesthesia.
  • Must be obtained early in course of disease before chronic inflammatory changes occur.
  • Exercise caution if:
    • Bleeding disorders or concurrent medication, eg aspirin Acetyl salicylic acid or anticoagulants Heparin Warfarin affecting bleeding.
    • Immunosuppressed animals: rare (may be wound healing problem).
    • Local anesthesia Local anesthesia: overview : injecting lidocaine with adrenalin near extremities and into patients with circulatory disorders (maximum 1 ml of 2% lidocaine Lidocaine /5 kg bodyweight).

Requirements

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Preparation

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Procedure

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Aftercare

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Rizzo L B, Ritchey J W, Higbee R G et al (2004) Histologic comparison of skin biopsy specimens collected by use of carbon dioxide or 810-nm diode lasers from dogs. JAVMA 225 (10), 1562-1566 PubMed.

Other sources of information

  • Ihrke P J (1996)Bacterial Skin Disease in the Dog - a Guide to Canine Pyoderma.Veterinary Learning Systems. pp 59-61 (Biopsy technique with special reference to pyoderma).
  • Moriello K A & Mason I S (eds) (1995)Handbook of Small Animal Dermatology. 1st edn. Pergamon. pp 31-33 (Step by step proceedure with photographs.)
  • Muller G Het al(1995)Muller and Kirk's Small Animal Dermatology.5th edn. Philadelphia: W B Saunders. pp 111-118 (Detailed account).


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