Canis ISSN: 2398-2942

Pleural fluid: differential cell count

Contributor(s): Vetstream Ltd

Overview

  • Normally minimal amount of pleural fluid present.
  • The number and type of cells found in pleural fluid varies with different conditions.
  • Inflammation increases cell count.
  • Cellularity generally increases in cases of modified transudates, eg heart disease, neoplasia, and particularly inflammatory exudates Pleural: effusion.

Sampling

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Tests

Methodologies

  • Total cell count by electronic or hemocytometer chamber as for WBC Hematology: leukocyte (WBC).
  • Direct Giemsa or Diff-Quick smear for cytomorphology - examine edges and feathered ends of smears.

Availability

  • Widely available.
  • Can be performed in practice laboratory.

Technique (intrinsic) limitations

  • Clumping or fragmentation of cells may distort count.

Technician (extrinsic) limitations

  • Contamination of sample with blood may obscure the cell count.

Result Data

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Further Reading

Publications

Refereed papers

Other sources of information

  • Willard M D (1989) Fluid Accumulation Disorders in Small Animal Clinical Diagnosis by Laboratory Methods. Chapter 10, pp 229-242. 1st edn. Eds Willard, Tvedten & Turnwald, W B Saunders.


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