Canis ISSN: 2398-2942

Hematology: band neutrophil, band cell

Contributor(s): Kathleen P Freeman

Overview

  • Immature, unsegmented neutrophils normally found circulating in small numbers.
  • Assess numbers relative to mature neutrophil count:
    • Regenerative left shift: mature neutrophils Hematology: neutrophil outnumber bands and are elevated or normal.
    • Degenerative left shift: excessive neutophil consumption → bands and/or less mature leukocytes outnumber mature neutrophils.
  • Neutrophils are short-lived (approximately 4 days).
  • Recognized by classic U-shaped nucleus or nucleus with indentations <50% of the width of the nucleus. May see horseshoe or S-forms.

Sampling

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Tests

Methodologies

  • Manual hemocytometer - accuracy +/- 20%.
  • Electronic counting systems - accuracy +/- 3-5% (intralaboratory); +/- 10-15% (interlaboratory).
  • QBC-V ( quantitative Buffy Coat analysis) hematology system.

Availability

  • Widely available at commercial laboratories.
  • May be performed in practice.

Validity

Sensitivity

  • Sensitive.

Specificity

  • Non-specific.

Predictive value

  • Useful if used in conjunction with differential white blood cell counts.

Technician (extrinsic) limitations

  • Some experience is required for accurate identification of leukocytes.

Result Data

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Further Reading

Publications

Refereed papers

Other sources of information

  • Cowell R L, Tyler R D & Meinkoth J H (1999) Diagnostic Cytology and Hematology of the Dog and Cat. 2nd edn. Mosby, St Louis.
  • Duncan J R, Prasse K W & Mahaffy E A (1994) Veterinary Laboratory Medicine Clinical Pathology. 3rd edn. Iowa University Press, Ames, Iowa.
  • Jain N C (1993) Essentials of Veterinary Hematology. Lea & Febiger, Philadelphia.


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