Canis ISSN: 2398-2942

Glucose tolerance test

Synonym(s): oral glucose tolerance, intravenous glucose tolerance

Contributor(s): Vetstream Ltd

Overview

Sampling

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Tests

Availability

  • Glucose assays widely available.
  • Glucometers available in practice Glucometer.

Technique (intrinsic) limitations

  • There is always a risk of life-threatening hypoglycemia developing on glucose challenge in animals with hyperinsulinemia.
  • Sudden rises in [plasma glucose] stimulate massive insulin secretion.

Technician (extrinsic) limitations

  • Shortened tests which are run over normal working day can miss significant hyperglycemia overnight. As a minimum a 2-3 hour post-prandial sample should be taken after evening meal.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Rottires R, Mattheeuws D, Kaneko J J & Vermeulen A (1981) Glucose uptake and insulin secretory responses to intravenous glucose loads in the dog. JAAHA 16, 695-698.
  • Kaneko J J, Mattheeuws D, Rotties R P & Vermeulen (1977) Glucose tolerance and insulin response in diabetes mellitus of dogs. JSAP 18, 85-94.
  • Butterfield W V H, Abrams M E & Whichelow M J (1971) The 25 g intravenous glucose tolerance test; a critical appraisal. Metabolism 20, 255-265.


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