Canis ISSN: 2398-2942

Fractional electrolyte excretion

Synonym(s): Urine fractional excretion

Contributor(s): Penney Barber, Kathleen P Freeman, Ludovic Pelligand

Overview

  • The clinical use of excretion fraction is limited but on occasion, these tests may be cost-effective when prioritizing renal investigations.
  • See also iohexal and creatinine clearances for estimation of GFR Creatinine clearance.
  • Plasma concentrations of electrolytes stay within normal range until renal failure advanced.

Sampling

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Tests

Methodologies

  • FE electrolyte % = ((Urine [electrolyte] x serum [creatinine])/(Urine [creatinine] x serum [electrolyte])) x 100.

Availability

  • Widely available through most commercial laboratories.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Brown N, Sevev G, Francey T, Kass P & Cowgill L (2015) Glomerular filtration rate, urine production, and fractional clearance of electrolytes in acute kidney injury in dogs and their association with survival. JVIM 29, 28-34 PubMed.
  • Pressler B (2013) Clinical approach to advanced renal function testing in dogs and cats. Vet Clin Small Anim 43, 1193-1208 PubMed.

Other sources of information

  • Dibartola S P (2005) Renal disease: clinical approach and laboratory evaluation. In: Textbook of Veterinary Medicine. S J Ettinger & E C Feldman (eds). pp 1716-1730.


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