Canis ISSN: 2398-2942
Blood biochemistry: triglycerides
Contributor(s): Kathleen P Freeman
Overview
- Most common form in which lipid is stored.
- Synthesized in:
- Intestinal mucosa (exogenous triglyceride) → carried to tissues as chylomicrons.
- Liver (endogenous triglyceride) → carried to tissues as very low density lipoproteins (VLDL).
- Both forms hydrolyzed in capillary endothelium by lipoprotein lipase (LDL) and free fatty acids → taken into cells.
- LDL activity increased by insulin, glucagon and thyroid hormones → lipemia may indicate decreased activity of one of these hormones.
- Cloudy serum is caused by hypertriglyceridemia.
Sampling
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Tests
Methodologies
- Spectrophotometric or enzymatic method: breaks down triglyceride and measures glycerol produced.
Availability
Technique (intrinsic) limitations
- Results only significant when interpreted in conjunction with other laboratory results.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from VetMed Resource and PubMed.
- Chikamune T (1998) Lipoprotein profile in canine pancreatitis induced with oleic acid. J Vet Med Sci 60(4), 413-421.
- Ford R B (1993) Ideopathic hyperchylomicronemia in Miniature Schnauzers. JSAP 39, 488.
- Watson T D & Barrie J Lipoprotein metabolism and hyperlipidemia in the dog and cat. JSAP 34, 479 (Review).
Other sources of information
- Ettiger S J & Feldman E C (2000) Textbook of Veterinary Internal Medicine. 5th edn. Philadelphi: Saunders and Co.
- Kaneko J J, Harvey J W & Brass M L (eds) (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Boston: Academic Press.
- Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa: Iowa University Press.