Canis ISSN: 2398-2942

Blood biochemistry: total calcium

Synonym(s): Ca

Contributor(s): Kathleen P Freeman

Overview

  • Major constituent of bones and teeth.
  • Physiological functions include nerve transmission and blood clotting.
  • Regulated by parathyroid hormone, calcitonin and vitamin D.
  • Important marker of bone disease and parathyroid function.
  • Comprises three fractions: ionized Blood biochemistry: ionized calcium (50%, biologically active), protein bound (40%) and chelated to anions (10%).
    Follow the diagnostic tree for Elevations in Total Serum Calcium Diagnostic tree: Elevations in Total Serum Calcium.

Sampling

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Tests

Methodologies

  • Colorimetric assay most commonly used.
  • May be measured directly by atomic absorption.

Availability

  • Routine availability at commercial laboratories.

Technique (intrinsic) limitations

  • Test results only significant in conjunction with other laboratory results and clinical findings.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Dhupa N, Proulx J (1998) Hypocalcemia and hypomagnesemia. Vet Clin North Am Small Anim Pract 28(3), 587-608.
  • Weir E C et al (1988) Humoral hypercalcemia of malignancy in canine lymphosarcoma. Endocrinology 122(2), 602-608.

Other sources of information

  • Ettinger S J & Feldman E C (eds) (2000) Textbook of Veterinary Internal Medicine. 5th edn. Philadelphia: W B Saunders & Co.
  • Kaneko J J, Harvey J W & Brass M L (eds) (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Boston: Academic Press.
  • Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa: Iowa University Press.


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