Canis ISSN: 2398-2942
Blood biochemistry: lactate dehydrogenase
Synonym(s): LD, Serum LDH, SLDH
Contributor(s): Vetstream Ltd
Overview
- Comprises 5 isoenzymes found principally in skeletal muscle, cardiac muscle, liver and red blood cells - not organ specific, but may be useful in assessment of muscle damage.
- LDH, and LDH2 - heart, RBCS, kidney, CNS.
- LDH3 - lung, pancreas, adrenal, spleen, thyroid gland.
- LDH4, and LDH5 - skeletal muscle, liver.
- Longer half-life than creatine phosphokinase Blood biochemistry: creatine phosphokinase.
Sampling
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Tests
Methodologies
- Varies between laboratories (electrophoresis needed for LDH isoenzymes).
Availability
Validity
Specificity
LDH without isoenzymes is so non-specific that it is rarely interpretatively useful.
Technique (intrinsic) limitations
- Test results most useful when interpreted in conjunction with other laboratory results and clinical findings.
Result Data
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Further Reading
Publications
Refereed papers
Other sources of information
- Kaneko J J (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Eds: J W Harvey & M L Bruss. Academic Press, Boston.