Canis ISSN: 2398-2942

Blood biochemistry: cholesterol

Contributor(s): Kathleen P Freeman

Overview

  • Major lipid in body and precursor of all steroid hormones and bile acids.
  • Obtained from diet and synthesized in liver.

Sampling

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Tests

Methodologies

  • Enzymatic method most common.
  • Cholesterolesterase (hydrolises cholesterol esters) and cholesteroloxidase are key enzymes.
  • If cholesterolesterase included total cholesterol is measured.
  • If cholesterolesterase not included non-esterified or 'free' cholesterol is measured.

Availability

  • Widely available at commercial laboratories.

Technique (intrinsic) limitations

  • Results only significant in conjunction with other laboratory results.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMedResource and PubMed.
  • Chikamune T (1998) Lipoprotein profile in canine pancreatitis induced with oleic acid. J Vet Med Sci 60(4), 413-421.
  • Ford R B (1993) Ideopathic hyperchylomicronaemia in Miniature Schnauzers. JSAP 39, 488.
  • Watson T D G & Barrie J (1993) Metabolism and hyperlipidemia in the dog and cat. A review. JSAP 34, 479.

Other sources of information

  • Ettinger S J & Feldman E C (eds) (2000) Textbook of Veterinary Internal Medicine. 5th edn. Philadelphia: W B Saunders & Co.
  • Kaneko J J, Harvey J W & Brass M L (eds) (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Boston: Academic Press.
  • Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa: Iowa University Press.


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