Canis ISSN: 2398-2942

Blood biochemistry: amylase

Synonym(s): Alpha Amylase, AMS

Contributor(s): Kathleen P Freeman

Overview

  • Plasma levels derived mainly from small intestine (duodenal mucosa), liver and pancreas → excreted through kidneys.
  • Inflammation of pancreas release large amounts.

Sampling

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Tests

Methodologies

  • Amyloclastic method.
  • Saccharogenic methods not appropriate for use on canine serum.

Availability

  • Widely available.

Validity

Sensitivity

  • Considered sensitive for canine pancreatitis but false negative and false positive results may occur.

Specificity

  • Not as specific for pancreatitis as lipase or TLI Blood biochemistry: lipase.
  • May see increases commonly with renal failure, gastrointestinal disease, and/or hepatobiliary disease.

Technique (intrinsic) limitations

  • Results most significant in conjunction with other laboratory results and clinical findings.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMedResource and PubMed.
  • Simpson K W, Batt R M, McLean L et al (1989) Circulating concetrations of trypsin-like immunoreactivity and activities of lipase and amylase after pancreatic duct ligation in dogs. Am J Vet Res 50, 629.
  • Hall T A & Macy D W (1988) Acute pancreatitis. Comp Cont Educ Pract Vet 10, 403.

Other sources of information

  • Ettinger S J & Feldman E C (eds) (2000) Textbook of Veterinary Internal Medicine.5th edn. Philadelphia: W B Saunders & Co.
  • Kaneko J J, Harvey J W & Brass M L (eds) (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Boston: Academic Press.
  • Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa: Iowa University Press.


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