Canis ISSN: 2398-2942

ACTH Assay

Contributor(s): Helen Evans, David Bruyette

Overview

  • ACTH is a peptide hormone secreted by the pituitary gland.
  • Regulates production of steroid hormones from adrenal cortex.
  • Secreted in pulsatile manner.
  • Little overlap between [ACTH] in dogs with PDH and ADH.
  • Useful discriminatory test once diagnosis of hyperadrenocorticism made.

Sampling

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Tests

Technique (intrinsic) limitations

  • Some overlap in [ACTH] between normal and hyperadrenocorticoid dogs.

Technician (extrinsic) limitations

  • Lability of hormone necessitates care in handling sample.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMedResource and PubMed.
  • Gould S M, Baines E A, Mannion P A, Evans H & Herrtage M E (2001) Use of endogenous ACTH concentration and adrenal ultrasonography to distinguish the cause of canine hyperadrenocorticism. JSAP 42, 113-121 PubMed.


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