Canis ISSN: 2398-2942

Zinc gluconate (for nonsurgical sterilization in the male dog)

Contributor(s): Autumn P Davidson, Vetstream Ltd

Introduction

Name

  • Zinc gluconate neutralized with arginine.

Class of drug

  • Zinc salt.

Description

Molecular formula

  • C12H22O14Zn.

Molecular weight

  • 455.685g.

Physical properties

  • White crystalline powder.
  • Preparations for intratesticular injection is aqueous solution.

Storage requirements

  • Store at room temperature 15-30°C.

Uses

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Indications

  • To produce chemical castration in healthy 3-10 month old male dogs.

Administration

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Precautions

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Interactions

with diagnostic tests

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from VetMed Resource and PubMed.
  • Wikler M, Pearson L K, Campbell A J, Tibary A. (2014)Non-surgical methods of contraception and sterilization in select domestic and wildlife species.Cl Theriogenology6(2), 93-104.
  • Forzán M J, Garde E, Pérez G E, Vanderstichel R V (2013)Necrosuppurative Orchitis and Scrotal Necrotizing Dermatitis Following Intratesticular Administration of Zinc Gluconate Neutralized With Arginine (EsterilSol) in 2 Mixed-Breed Dogs.Vet Pathol 51 (4), 820-823PubMed.
  • Oliveira E C, Moura M R, de Sá M J, Silva V A Jr, Kastelic J P, Douglas R H, Marques A P Jr (2012)Permanent contraception of dogs induced with intratesticular injection of a Zinc Gluconate-based solution.Theriogenology77(6), 1056-1063PubMed.
  • Levy J K, Crawford P C, Appel L D, Clifford E L (2008)Comparison of intratesticular injection of zinc gluconate versus surgical castration to sterilize male dogs.Am J Vet Res69(1), 140-143PubMed.

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