Canis ISSN: 2398-2942

Ticarcillin

Introduction

Name

  • Ticarcillin.

Class of drug

  • Carboxypenicillin antibiotic.

Description

Storage requirements

  • After reconstitution it is stable for 48-72 hours.

Uses

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Indications

  • Principally indicated for the treatment of serious (usually but not exclusively life threatening) Pseudomonas aeruginosa Pseudomonas aeruginosa infections.
  • For pseudomonas septicaemias ticarillin should be given with an aminoglycoside, eg gentamicin Gentamicin.
  • Activity against certain other gram-negative bacilli including Proteusspp Proteus spp and Bacteroides fragilis Bacteroides fragilis.

Administration

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Precautions

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Interactions

with other drugs



Aminoglycosides
  • Do not mix with ticarcillin because there is mutual inactivation.
  • Use with ticarcillin for pseudomonas septicemias as there is a synergistic effect.

    Do not mix in the same syringe.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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