ISSN 2398-2942      

Tetracycline

icanis
Contributor(s):

Introduction

Name

  • Tetracycline.

Class of drug

  • Tetracycline antibiotic.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • A bacteriostatic antibiotic which inhibits the growth of many gram-positive and gram-negative bacteria, several rickettsiae, mycoplasma Mycoplasmas and ureaplasmas , spirochaetes Borrelia burgdorferi (Lyme disease Arthritis: borrelial ) and other microbes.
  • Tetracycline differs from oxytetracycline Oxytetracycline in its lipid solubility (oxytetracycline low solubility, tetracycline intermediate solubility) although this is unlikely to be of clinical relevance.
  • Ophthalmic tetracycline is the preferred agent for the treatment of chlamydia, mycoplasma or rickettsial eye infections.
  • Tetracycline is also used to cause pleurodesis.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs



Penicillins
  • The bactericidal action of the penicillins may be inhibited by bacteriostatic antibiotics.
Drugs inhibiting absorption of orally administered tetracyclines
  • Antacids containing divalent or trivalent cations (magnesium, calcium, aluminium).
  • Iron Iron.
  • Oral sodium bicarbonate Sodium bicarbonate.
Digoxin
  • The bioavailability of digoxin Digoxin may be increased by tetracyclines for months after their discontinuation. This may lead to digoxin toxicity.
Anticoagulants
  • Plasma prothrombin activity may be decreased by tetracyclines and therefore patients on anticoagulant therapy may need a dose adjustment.
Methoxyflurane
  • Tetracyclines may increase the nephrotoxic effects of methoxyflurane Methoxyflurane.
Theophyllines
  • The gastrointestinal (GI) effects of tetracyclines may be increased.

with diagnostic tests

  • Plasma prothrombin activity may be decreased.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant B (1999) 3rd edn. BSAVA, UK.
MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code