Canis ISSN: 2398-2942

Sotalol

Contributor(s): Craig Devine, Jill Sammarco

Introduction

Name

  • Sotalol.

Class of drug

  • Anti-arrhythmic (non-selective ß-adrenergic blocking drug with potassium channel blocking effects - classified as type III anti-arrhythmic under the Vaughan Williams classification).

Description

Chemical name

  • Sotalol HCL (racemic mixture ofd-andl-stereo-isomers).

Physical properties

  • White crystalline solid.
  • Soluble in water.

Storage requirements

  • Store at room temperature.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Used for the treatment of ventricular tachycardias Ventricular tachycardia in dogs.
  • Treatment of Boxers Boxer with severe ventricular tachycardias and syncope.
  • Other indications may include the management of supraventricular tachycardias including atrioventricular nodal independent supraventricular tachycardia and atrioventricular reciprocating tachycardia associated with atrioventricular accessory pathways.
  • Atrial fibrillation Heart: atrial fibrillation and atrial flutter.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmocokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Meurs K Met al(2002)Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.J Am Vet Med Assoc221(4),522 - 527.PubMed
  • Wright K N (2000)Assessment and Treatment of Supraventricular tachyarrhythmias.Kirk's Current Veterinary Therapy XIII - Sm Anim Pract.726 - 730.
  • Atkins C E & Wright K N (1995)Supraventricular tachycardia associated with accessory atrioventricular pathways in dogs.Kirk's Current Veterinary Therapy XII - Sm Anim Pract.807 - 813.

Other sources of information

  • Moise S N (2002)Chronic management of tachyarrhythmias in the dog.Proceedings from the 26th Annual Waltham Symposium.
  • Plumb D C (2002)Veterinary Drug Handbook, Fourth Edition.Pharma Vet Publishing, Minnesota.
  • Braunwald E, Zipes D P& Libby P (2001)Heart Disease: A Textbook of Cardiovascular Medicine. 6th Edn.W B Saunders Co, Philadelphia.
  • Fox P R, Sisson D & Moise N S (1999)Textbook of Canine and Feline Cardiology: principles and clinical practice. 2nd edn.W B Saunders Co, Pennsylvania.
  • Kittleson M D & Kienle R D (1998)Small Animal Cardiovascular Medicine.Mosby, St Louis.

ADDED