Canis ISSN: 2398-2942

Propofol

Contributor(s): Sheilah Robertson

Introduction

Name

  • Propofol.

Class of drug

  • Ultra short-acting phenolic intravenous anesthetic.

Description

Storage requirements

  • Once a vial or bottle is opened it must be used or discarded within 4-12 hours due to danger of bacterial growth in the emulsion.

Uses

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Indications

Administration

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Pharmocokinetics

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Musk G C, Pang D S J, Beths T & Flaherty D A (2005)Target-controlled infusion of propofol in dogs - evaluation of four targets for induction of anaesthesia.Vet Rec157, 766-770.
  • Murrell J C, Wesselink van Notten R & Hellebrekers L J (2005)Clinical investigation of remifentanil and propofol for the total intravenous anaesthesia of dogs.Vet Rec156, 804-808.
  • Steffen F & Grasmueck S (2000)Propofol for treatment of refractory seizures in dogs.JSAP41(11), 496-499.
  • Heldmann Eet al(1999)Use of propofol to manage seizure activity after surgical treatment of portosystemic shunts.JSAP40(12), 590-4.
  • Davies C (1991)Excitatory phenoma following the use of propofol in dogs.J Vet Anaesth18, 48-51.

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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