ISSN 2398-2942      

Prochlorperazine

icanis

Introduction

Name

  • Prochlorperazine.

Class of drug

  • Piperazine phenothiazine.
  • CNS dopamine receptor blocker.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • It is used predominantly to control motion sickness.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs

CNS depressant agents, eg anesthetics, narcotic analgesics

  • May cause additive CNS depression.

Quinidine

  • Given with phenothiazines may cause additive cardiac depression Quinidine.

Antacids or antidiarrheal preparations, eg bismuth subsalicylate or kaolin/pectin mixtures

  • May reduce gastrointestinal absorption of oral phenothiazines Aluminum antacid.

Propranolol

  • Increased blood levels of both drugs may result if propranolol Propranolol is administered with phenothiazines.

Epinephrine

  • Phenothiazines block alpha-adrenergic receptors which, may lead to unopposed beta activity causing vasodilation and increased cardiac rate Epinephrine.

Phenytoin

  • Phenytoin Phenytoin : metabolism may be decreased if given concurrently with phenothiazines.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant B (1999) 3rd edn. BSAVA, UK.
MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code