Canis ISSN: 2398-2942

Octreotide

Introduction

Name

• Octreotide.

Class of drug

• A long-acting analog of the hypothalamic hormone somatostatin.

Description

Chemical name

• D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2->7)-disulfide.

Molecular formula

• C49H66N10O10S2.

Molecular weight

• 1019.26.

Uses

Indications

• May be useful in the management of gastric, enteric and pancreatic endocrine tumors, eg insulinoma Pancreas: neoplasia: insulinoma , gastrinoma Pancreas: neoplasia: gastrinoma and acromegaly Acromegaly although variable responses have been reported in veterinary medicine.
• Tumors not expressing somatostatin receptors will not respond.

Administration

Adverse Reactions