Canis ISSN: 2398-2942

Metronidazole

Introduction

Name

  • Metronidazole.

Class of drug

  • Synthetic nitroimidazole.

Description

Chemical name

  • 2-methyl-5-nitroimidazole-1-ethanol.

Molecular formula

  • C6H9N3O3.

Physical properties

  • Sterile, aqueous solution.
  • Tablets.

Storage requirements

  • Protect from light.
  • <25°C.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

With other drugs

Phenobarbitone or phenytoin Cimetidine
  • May decrease metabolism of metronidazole and increase the likelihood of dose-related adverse effects occurring Cimetidine.

with diagnostic tests

  • The one-stage prothrombin (OSPT) time in patients on warfarin may be prolonged by metronidazole.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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