Canis ISSN: 2398-2942

Ketamine

Contributor(s): John Dodam, Sheilah Robertson

Introduction

Name

  • Ketamine.

Class of drug

  • Cyclohexanone derivative.
  • N-methyl-D-aspartate receptor antagonist.

Description

Chemical name

  • (+/-)-2-(2-chlorophenyl)-2-(methylamino)cyclohexanone.

Molecular formula

  • C13H16ClNO.

Physical properties

  • Clear solution.

Storage requirements

Uses

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Indications

  • A dissociative anesthetic/analgesic used to provide restraint or dissociative anesthesia.
  • Dissociative anesthesia is associated with mild stimulation of cardiac output and blood pressure, modest respiratory depression and preservation of cranial nerve reflexes.
    Eyes remain open during anesthesia. Bland ophthalmic lubricant should be used.
  • Useful in reptiles, particularly those who 'breath hold'.
    Ketamine alone does not provide sufficient analgesia for ovariohysterectomy Ovariohysterectomy.

Administration

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Precautions

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Adverse Reactions

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Further Reading

Publications

Referred papers

Other sources of information

  • Based on Tennant B (1999) Small Animal Formulary. 3rd edn. Cheltenham: BSAVA.

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