Canis ISSN: 2398-2942

Itraconazole

Contributor(s): Rosanna Marsella

Introduction

Name

  • Itraconazole.

Class of drug

  • Triazol antifungal.

Description

Physical properties

  • Lipophilic.

Storage requirements

  • Store capsules at room temperature protected from light and moisture.
  • Oral suspension stored in refrigerator for up to one month.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs



Antacids, H2 antagonists and adsorbents
  • May reduce the absorption of itraconazole Aluminum antacid.
  • In man may inhibit metabolism of antihistamines by inhibiting cytochrome P450, oral hypoglycaemics, anti-epileptics, cisapride and cyclosporine.
  • The significance of these interactions in veterinary species has not been studied.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Legendre A Met al(1996)Treatment of blasomycosis with itraconazole in 112 dogs.J Vet Intern Med10(6), 365-371.

Other sources of information

  • Based on Tennant B (1999)Small Animal Formulary.3rd edn. Cheltenham: BSAVA.

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