ISSN 2398-2942      

Hydromorphone

icanis
Contributor(s):

John Dodam

Vetstream Ltd


Introduction

Name

  • Hydromorphone.

Class of drug

Description

Chemical name

  • Hydromorphone hydrochloride.

Molecular formula

  • 4,5±-Epoxy-3-hydroxy-17-methylmorphinan-6-one hydrochloride.

Molecular weight

  • 321.80.

Physical properties

  • White powder that is freely soluble in water.
  • Semi-synthetic phenanthrene alkaloid of opium.

Storage requirements

  • Store at 15-30°C.
  • Protect from light.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • For the relief of pain.
  • Can be used pre-emptively for elective surgical procedures.
  • Can be used to relieve pain from trauma Trauma: overview.
  • Has also been used to provide longer-term pain relief, for example that caused by osteosarcoma Osteosarcoma.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

with other drugs

  • Can cause profound sedation when combined with acepromazine Acepromazine maleate , alpha2-agonists (xylazine Xylazine , medetomidine Medetomidine ) and benzodiazepines.
  • Hydromorphone may reduce the induction dose of injectable anesthetic agents and lower the dose of inhalant agents required for maintenance of anesthesia.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Pettifer G & Dyson D (2000) Hydromorphone: a cost-effective alternative to the use of oxymorphone.​ Can Vet J 41 (2), 135-137 PubMed.

Other sources of information

  • Pascoe P J (2000) Opioid Analgesics. In: Management of Pain. Vet Clin North Am Small An Pract 30 (4), 757-772.
MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code