Canis ISSN: 2398-2942

Halothane

Contributor(s): Sheilah Robertson

Introduction

Name

  • Halothane.

Class of drug

  • Inhalational general anesthetic.

Description

Chemical name

  • Halothane: halogenated, aliphatic saturated hydrocarbon containing bromine, chlorine and fluorine.
  • 2-bromo-2-chloro-1,1,1-trifluoroethane.

Molecular formula

  • C2HBrClF3.

Physical properties

  • Heavy liquid.

Storage requirements

  • Keep below 40°C.
  • Keep away from light.

Uses

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Indications

  • Inhalational anesthetic General anesthesia: overview.
  • Potent and highly volatile so should be delivered only through a calibrated vaporizer.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs



Epinephrine and thiobarbiturates
  • Increased risk of arrhythmia.
Opioid agonists, benzodiazepines, and nitrous oxide
  • Reduce concentration of halothane required to achieve surgical anesthesia.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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