Canis ISSN: 2398-2942

Fluticasone

Contributor(s): Elizabeth Rozanski

Introduction

Name

  • Fluticasone propionate.

Class of drug

  • Corticosteroid.

Description

Chemical name

  • S-(fluoromethyl) 6alpha,9-difluoro-11beta,17-dihydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carbothioate-17-propionate.

Molecular formula

  • C25H31F3O5S.

Molecular weight

  • 500.57.

Physical properties

  • White powder insoluble in water.

Storage requirements

  • Do not store >30°C (86°F).
  • Do not refrigerate or freeze.
  • Protect from frost and direct sunlight.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

with diagnostic tests

  • Endogenous cortisol levels may be suppressed during treatment with fluticasone.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references fromVetMedResourceandPubMed.
  • Cohn L A, DeClue A E, Reinero C R (2008)Endocrine and immunologic effects of inhaled fluticasone propionate in healthy dogs.J Vet Intern Med22(1), 37-43PubMed.
  • Bexfield N H, Foale R D, Davison L J, Watson P J, Skelly B J, Herrtage M E (2006)Management of 13 cases of canine respiratory disease using inhaled corticosteroids.J Small Anim Pract 47, 377-382PubMed.
  • Padrid P (2006)Use of inhaled medications to treat respiratory diseases in dogs and cats.J Am Anim Hosp Assoc42(2), 165-169.

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