Canis ISSN: 2398-2942

Fluorouracil

Synonym(s): 5-FU

Contributor(s): William Brewer Jr

Introduction

Name

  • Fluorouracil.

Class of drug

  • Antineoplastic pyrimidine analogue.

Description

Chemical name

  • 5-fluoro-2,4(1H,3H)-pyrimidinedione.

Molecular formula

  • C4H3FN2O2.

Physical properties

  • Solution.
  • Cream.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

Allopurinol Allopurinol

  • Decreases hepatic activation.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Fischer D S, Knobf M Tet al(2003)The Cancer Chemotherapy Handbook. 6th edn. Philadelphia, PA, Mosby. pp 128-130.
  • Based onSmall Animal Formulary.Tennant B (1999) 3rd edn. Cheltenham: BSAVA.

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