Canis ISSN: 2398-2942

Florfenicol

Synonym(s): Fluorinated synthetic analogue of the antibiotic thiamphenicol

Contributor(s): Vetstream Ltd, Sue Paterson

Introduction

Name

  • Florfenicol amine.

Class of drug

  • Fluorinated synthetic analogue of the antibiotic thiamphenicol. 

Description

Chemical name

  • (1R,2S)-2-amino-3-fluoro-1-(4-methylsulfonylphenyl)propan-1-ol.

Molecular formula

  • C₁₂H₁₄Cl₂FNO₄S

Molecular weight

  • 358.21

Physical properties

  • Topical gel.

Storage requirements

  • Refrigerator.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

With other drugs

  • Interaction with other drugs has not been recognized.
Neither product should be used if the ear drum is ruptured.

Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from VetMed Resource and PubMed.
  • Forster S L, Real T, Doucette K P, King S B (2018) A randomized placebo-controlled trial of the efficacy and safety of a terbinafine, florfenicol and betamethasone topical ear formulation in dogs for the treatment of bacterial and/or fungal otitis. BMC Vet Res 14(1), 1-11 PubMed.
  • King S B, Doucette K P, Seewald W, Forster S L (2018) A randomized, controlled, single-blinded multi-centre evaluation of the efficacy and safety of a once weekly two dose otic gel containing florfenicol, terbinafine and betamethasone administered for the treatment of canine otitis externa. BMC Vet Res 14(1), 1-9 PubMed.

Other sources of information


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