Canis ISSN: 2398-2942

Filgrastim

Synonym(s): Neopogen

Contributor(s): Vetstream Ltd

Introduction

Name

  • Filgrastim (G-CSF).

Class of drug

  • Recombinant human granulocyte-colony stimulating factor.
  • Glycoprotein produced by bone marrow, stromal cells, monocytes/macrophages, fibroblasts and endothelial cells.

Uses

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Indications

  • Indicated in the management of neutropenia. Neutrophil counts rise within 24 hours. Following discontinuation of therapy, neutrophil counts drop to normal after 5 days.
  • Most likely to be used in febrile patients with neutrophil counts of less than 1x10*9/l.

Administration

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn. Cheltenham: BSAVA.

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