Canis ISSN: 2398-2942

DOCP (US)

Synonym(s): Percorten-V; Desoxycortone pivalate

Contributor(s): Vetstream Ltd

Introduction

Name

  • DOCP

Class of drug

Description

Chemical name

  • 21 (2,2-dimethyl-1-oxopropoxy)-pregn-4-ene-3,20-dione

Molecular formula

  • C26 H38 O4

Molecular weight

  • 414.58

Physical properties

  • White odorless microcrystals.
  • Stable in air.
  • Soluble in methanol, ether and vegetable oils.

Storage requirements

  • Store at room temperature, preferably 15 - 30 degrees C (59 - 86 degrees F).
  • Protect from light.
  • Protect from freezing.

Uses

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Indications

  • Adrenocortical insufficiency (Addison's disease) Hypoadrenocorticism.
    It is essential to accurately diagnose primary canine adrenocortical insufficiency before administration.

Administration

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Pharmocokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Lynn and Feldman (1991) Treatment of Canine Hypoadrenocorticism with Microcrystalline Desoxycorticosterone Pivalate. British Veterinary Journal 147, 478-483.
  • Lynn, et al (1993) Efficacy of Microcrystalline Desoxycorticosterone Pivalate for Treatment of Hypoadrenocorticism in Dogs. Journal of American Veterinary Medical Association 202(3), 392-396.
  • MacCabe, et al (1995) Subcutaneous Administration of Desoxycorticosterone Pivalate for the Treatment of Canine Hypoadrenocorticism. Journal of the American Animal Hospital Association 31, 151-155.

Other sources of information


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