Canis ISSN: 2398-2942

Dimethylsulfoxide

Synonym(s): DMSO

Introduction

Name

  • Dimethylsulfoxide.

Class of drug

  • Anti-inflammatory.

Uses

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Indications

  • Useful as a carrier to enhance absorption of other drugs through skin.
  • Otitis externa Skin: otitis externa (topical anti-inflammatory).
  • Management of hemorrhagic cystitis induced by cyclophosphamide Cyclophosphamide.
  • To decrease intra-cranial pressure (IV use) following central nervous system (CNS) trauma Brain: trauma.
  • Amyloidosis Amyloidosis (efficacy unproven).
  • Management of reperfusion injury, eg following gastric/intestinal torsion Stomach: gastric dilatation / volvulus (GDV) syndrome (free radical scavenger).
  • Must be administered prior to reperfusion to be effective.

Administration

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Precautions

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Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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