Canis ISSN: 2398-2942

Dextrans

Synonym(s): Gentran, Macrodex, Rheomacrodex, Dextran

Introduction

Name

  • Dextrans.

Class of drug

  • Macromolecular substances.

Uses

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Indications

  • Used to expand and maintain blood volume in shock due to septicemia Shock: septic and burns Fluid therapy: for burns.
  • May be used in the immediate short term to manage hemorrhage until blood is available Fluid therapy: for hemorrhage.
  • Rarely required when shock is due to water and sodium depletion.
  • Dextran 40 increase plasma volume by 50% at one hour and 110% at 2 hours. Dextran 70 increases plasma volume by 38%.

Administration

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Precautions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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