Canis ISSN: 2398-2942

Chlorothiazide

Introduction

Name

  • Chlorothiazide.

Class of drug

  • Thiazide diuretic.

Description

Chemical name

  • 6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide.

Molecular formula

  • C7H6ClN3O4S2.

Physical properties

  • Colorless.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs



Corticosteroids
  • Increased risk of hypokalemia.
Diazoxide
  • Concurrent administration may lead to hyperglycemia and hypotension.
Calcium salts or Vitamin D
  • Risk of hypercalcemia if thiazides are administered concurrently with calcium ot Vitamin D Vitamin D.
Sulfonamides
  • May potentiate thiazide activity.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

ADDED