Canis ISSN: 2398-2942

Ceftazidime

Synonym(s): Fortum*Kefadim*

Introduction

Name

  • Ceftazidime.

Class of drug

  • Antibiotic.

Uses

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Indications

  • Good activity againstPseudomonasspp Pseudomonas aeruginosa.
  • Use reserved for patients with acute sepsis or serious infections where cultures are pending and the animal is not a good candidate for intensive aminoglycoside therapy (pre-existing renal dysfunction).
  • Cephalosporins are particularly useful for the treatment of susceptible renal infections.

Administration

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Precautions

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Interactions

with other drugs



Antibiotics
  • The bactericidal activity of cephalosporins may be affected by the concomitant use of bacteriostatic agents (eg tetracycline Tetracycline , erythromycin Erythromycin ).
  • There may be an increased risk of nephrotoxicity if cephalosporins are used with amphotericin or loop diuretics (eg frusemide Furosemide ); monitor renal function.
  • Probenecid reduces the excretion of cephalosporins.

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA. ISBN: 0 905214 44 7.

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