Canis ISSN: 2398-2942

Cefalexin

Synonym(s): Cephalexin

Contributor(s): Stephen Barr

Introduction

Name

  • Cephalexin.

Class of drug

  • 1st generation cephalosporin antibiotic.
  • Member of beta-lactam group.

Description

Chemical name

  • [6R-[6-alpha,7-beta(R*]]-7-(aminophenylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

Molecular formula

  • C16H17N3O4S.

Physical properties

  • Oily suspension.
  • Granules.
  • Tablets.

Storage requirements

  • <25°C.
  • Protect from light.
  • Refrigeration preferable.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs



Bacteriostatic antibiotics
  • The bactericidal activity of cephalosporins may be affected by the concomitant use of bacteriostatic agents, eg erythromycin Erythromycin , tetracycline Tetracycline.
Amphotericin and loop diureticsProbenicid
  • Probenecid reduces the excretion of cephalosporins.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

ADDED