Canis ISSN: 2398-2942

Bismuth

Synonym(s): Pepto-Bismol

Contributor(s): Lauren Trepanier

Introduction

Name

  • Bismuth.

Class of drug

  • Cytoprotectant.

Description

Physical properties

  • Grayish-white with reddish tinge and bright metallic luster; soft and brittle.
  • Superficially oxidized by air; frequently becoming iridescent.
  • Melting point 271°C - contracts when melted.

Uses

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Indications

  • In man, bismuth chelate is effective in healing gastric and duodenal ulcers due to its direct toxic effects on gastricHelicobacter pylori Helicobacter spp and by stimulating prostaglandin or bicarbonate secretion.
  • It is often used in conjunction with an H2 antagonist and appropriate antibacterial therapy.

Administration

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Precautions

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Interactions

with other drugs



Tetracyclines
  • Absorption reduced by bismuth.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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