Canis ISSN: 2398-2942

Apraclonidine

Contributor(s): David Maggs

Introduction

Name

  • Apraclonidine hydrochloride.

Class of drug

  • Selective alpha-2 adrenoceptor agonist.

Uses

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Indications

  • In humans: control of intraocular pressure in glaucoma Glaucoma or following intraocular surgery.
  • In dogs: possible adjunct to other hypotensive agents.
  • In cats: contraindicated.
    Little information regarding efficacy in dog or cat.

Administration

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Pharmocokinetics

Precautions

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Interactions

with other drugs

  • In human concurrent use with MAO inhibitors is contraindicated.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Miller P E & Rhaesa S L (1996)Effects of topical administration of 0.5% apraclonidine on intraocular pressure, pupil size, and heart rate in clinically normal cats.Am J Vet Res57, 83-86.
  • Miller P E, Nelson M J & Rhaesa S L (1996)Effects of topical administration of 0.5% apraclonidine on intraocular pressure, pupil size, and heart rate in clinically normal dogs.Am J Vet Res57, 79-82.

Other sources of information

  • Bartlett J D (2000)Ophthalmic Drug Facts 2000. Facts and Comparisons.St Louis, MO.

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