Canis ISSN: 2398-2942

Apraclonidine

Contributor(s): David Maggs, Vetstream Ltd

Introduction

Name

  • Apraclonidine hydrochloride.

Class of drug

  • Selective alpha-2 adrenoceptor agonist.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • In humans: control of intraocular pressure in glaucoma Glaucoma or following intraocular surgery.
  • In dogs: possible adjunct to other hypotensive agents.
  • In cats: contraindicated.
    Little information regarding efficacy in dog or cat.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

  • In human concurrent use with MAO inhibitors is contraindicated.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Miller P E & Rhaesa S L (1996) Effects of topical administration of 0.5% apraclonidine on intraocular pressure, pupil size, and heart rate in clinically normal cats. Am J Vet Res 57 (1), 83-86 PubMed.
  • Miller P E, Nelson M J & Rhaesa S L (1996) Effects of topical administration of 0.5% apraclonidine on intraocular pressure, pupil size, and heart rate in clinically normal dogs. Am J  Vet Res 57 (1), 79-82 PubMed.

Other sources of information

  • BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn. Cheltenham: BSAVA.
  • Bartlett J D (2000) Ophthalmic Drug Facts 2000. Facts and Comparisons. St Louis, MO.

ADDED