Canis ISSN: 2398-2942

Amoxicillin

Synonym(s): Amoxycillin

Introduction

Name

  • Amoxycillin.

Class of drug

  • Penicillin antibiotic.

Description

Chemical name

  • 6[D(-)-a-amino-p-hydroxyphenylacetmido] penicillanic acid.

Molecular formula

  • C16H19N3O5S.

Physical properties

  • Tablets.
  • Acid-stable, beta-lactamase-susceptible.

Storage requirements

  • <25°C.
  • In a dry environment.

Uses

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Indications

  • Active against certain gram-positive and negative organisms.
  • Not active against those that produce penicillinases, egE. coli Escherichia coli andStaphylococcus aureus Staphylococcus spp.
  • The more difficult gram-negative organisms (Pseudomonas spp Pseudomonas andKlebsiella spp) are usually resistant.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs



Probenecid
  • Will decrease the renal tubular secretion of penicillin antibiotics Penicillamine and thus prolong their blood levels.
Aminoglycosides
  • Do not mix in the same syringe as aminoglycosides.

Adverse Reactions

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Further Reading

Publications

Other sources of information

  • Based onSmall Animal Formulary.Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.

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