ISSN 2398-2942      

Therapeutics: antimicrobial drug

icanis

Synonym(s): Antibiotic


Introduction

  • A number of factors should be taken into consideration when selecting an appropriate antimicrobial for use in dogs:
    • If the culture result is significant, the sensitivity will influence which therapeutic options are available; in the absence of this, consider which pathogens are likely to be involved and their susceptibility to antimicrobial agents.
      • Consider which antimicrobials are appropriate for use in dogs, and their relative safety.
      • Consider the ability of the antimicrobial to reach the required target tissue (eg the center of an abscess).
      • Finally, having decided on the antimicrobial agent to use, the methods at which it can be given need to be considered and a practical treatment plan formulated.
Many antimicrobials are not licensed in veterinary species and licensing varies across the world. It is advisable to check with the local authority prior to administration. See also Therapeutics: bacterial infection.

Antimicrobial agents which inhibit bacterial wall synthesis

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Antimicrobial agents which target the cell membrane

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Nucleic acid synthesis and repair inhibitors

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Drugs which inhibit protein synthesis

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Antifungal drugs

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Adams V J, Campbell J R, Waldner C L et al (2005) Evaluation of client compliance with short-term administration of antimicrobials to dogs. JAVMA 226 (4), 567-574 PubMed.
  • Grave K & Tanem H (1999) Compliance with short-term oral antibacterial drug treatment in dogs. JSAP 40 (4), 158-162 PubMed.
  • Barter L S, Watson A D & Maddison J E (1996) Owner compliance with short term antimicrobial medication in dogs. Aust Vet J 74 (4), 227-280 PubMed.

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