Canis ISSN: 2398-2942

Skin: atopy - anti-inflammatory therapy

Synonym(s): Atopic dermatitis management

Contributor(s): Tim Nuttall, David Godfrey

Introduction

Proactive therapy

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Integrated treatment programs

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Anti-inflammatory treatment options

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Acute and chronic atopic dermatitis

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Glucocorticoids

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Topical tacrolimus

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Ciclosporin (Atopica® capsules; Cyclavance® & Modulis® 100 mg/ml oral solutions; and Sporimmune® 50 mg/ml oral solution)

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Oclacitinib (Apoquel®)

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Lokivetmab (Cytopoint®)

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Michels G M, Ramsey D S, Walsh K F et al (2016) A blinded, randomized, placebo-controlled, dose determination trial of lokivetmab (ZTS-00103289), a caninized, anti-canine IL-31 monoclonal antibody in client owned dogs with atopic dermatitis. Vet Dermatol  27 (6), 478-e129 PubMed.
  • Panteri A, Strehlau G, Helbig R et al (2016) Repeated oral dose tolerance in dogs treated concomitantly with ciclosporin and oclacitinib for three weeks. Vet Dermatol 27 (1), 22-e67 PubMed.
  • Pucheu-Haston C M, Eisenschenk M N, Bizikova P et al (2015) Introduction to the review articles by ICADA on the pathogenesis of atopic dermatitis in dogs. Vet Dermatol 26 (2), 77-78 PubMed.
  • Olivry T, DeBoer D J, Favrot C et al (2015) Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA). BMC Vet Res 11, 210  PubMed.
  • Little P R, King V L, Davis K R et al (2015) A blinded, randomized clinical trial comparing the efficacy and safety of oclacitinib and ciclosporin for the control of atopic dermatitis in client-owned dogs. Vet Dermatol 26 (1), 23-30, e7-8 PubMed.
  • Nuttall T, Reece D, Roberts E (2014) Life-long diseases need life-long treatment: long-term safety of ciclosporin in canine atopic dermatitis. Vet Rec 174 (Suppl 2), 3-12 PubMed.
  • Dip R, Carmichael J, Letellier I et al (2013) Concurrent short-term use of prednisolone with cyclosporine A accelerates pruritus reduction and improvement in clinical scoring in dogs with atopic dermatitis. BMC Vet Res 9, 173 PubMed.


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