Canis ISSN: 2398-2942

Anesthetic induction: overview

Contributor(s): Jo Murrell, Sheilah Robertson

Introduction

  • General anesthesia: a state of unconsciousness produced by controlled, reversible intoxication of the central nervous system during which the patient neither perceives nor recalls noxious stimuli.
  • Anesthetic agent: a substance which produces loss of consciousness in a controllable manner.
  • Anesthetic induction: the state achieved when anesthetic agent concentration in the brain is high enough.
  • Induction can be achieved using (alone or in combination):
    • Injectable agents administered intravenously (IV) or intramuscularly (IM).
    • Volatile agents inhaled with a carrier gas.

Injectable Agents

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Volatile agents

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Ferr√© P J, Pasloske K, Whittem T et al (2009) Plasma pharmacokinetics of alfaxalone in dogs after an intravenous bolus of Alfaxan-CD RTU. Vet Anaesth Analg 33 (4), 229-236 PubMed.
  • Pasloske K, Sauer B, Perkins N et al (2009) Plasma pharmacokinetics of alfaxalone in both premedicated and unpremedicated Greyhound dogs after single, intravenous administration of Alfaxan at a clinical dose. J Vet Pharmacol Ther 32 (5), 510-513 PubMed.
  • Sams R A, Muir W W (1988) Effects of phenobarbital on thiopental pharmacokinetics in greyhounds. Am J Vet Res 49 (2), 245-249 PubMed.
  • Robinson E P, Sams R A, Muir W W (1986) Barbiturate anesthesia in greyhound and mixed-breed dogs: comparative cardiopulmonary effects, anesthetic effects, and recovery rates. Am J Vet Res 47 (10), 2105-2112 PubMed.
  • Sams R A, Muir W W, Detra R L et al (1985) Comparative pharmacokinetics and anesthetic effects of methohexital, pentobarbital, thiamylal, and thiopental in Greyhound dogs and non-Greyhound, mixed breed dogs. Am J Vet Res 46 (8), 1677-1683 PubMed.


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