Canis ISSN: 2398-2942

Anesthesia: in renal insufficiency

Contributor(s): John Dodam

General

  • Often overlooked.
  • Insidious onset - few days before signs appear.
  • Severe hypotensionmay compromize renal autoregulation/blood flow → prerenal failure.
  • Mean arterial blood pressure below 60 mmHg likely to compromise renal blood flow.
  • The management of anesthesia in patients with renal insufficiency is relatively simple and straightforward.
  • Hypotension should be avoided or treated aggressively when it occurs.
  • Drugs that are nephrotoxic should be avoided.
  • Drugs which maintain glomerular filtration or glomerular blood flow may also be included in the management of patients with renal disease, ie dopamine, mannitol.
  • Central venous pressure is frequently used to assess circulating volume.

Factors

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Management

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Further Reading

Publications

Refereed papers
  • Recent references fromPubMed.

Other sources of information

  • Finco D R, Brown S A, Barsanti J A et al(2000)Recent developments in the management of progressive renal failure.In: Current Veterinary XIIIEd J D Bonagura. W B Saunders, Philadelphia. pp 861-864.
  • Greene S A (1996)Renal diseaseIn: Lumb and Jones' Veterinary Anesthesia3rd ed. Eds J C Thurmon, W J Tranquilli & J G Benson. Williams and Wilkins, Baltimore. pp 785-790.


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