Canis ISSN: 2398-2942

Skin: thyroid-responsive alopecia

Introduction

  • Cause: hypothyroidism Hypothyroidism.
  • Signs: non-pruritic alopecia - tends to be bilaterally symmetrical.
  • Can be associated with other dermatological signs as well as alopecia.
  • Systemic signs may be present.
  • Diagnosis: see hypothyroidism Hypothyroidism to rule out other causes and then investigate possibility of hypothyroidism see flowchart Hypothyroidism diagnostic flowchart.
  • Treatment: responds well to thyroid hormone supplementation.
  • Prognosis: good.

Pathogenesis

Etiology

Pathophysiology

  • Thyroid hormones are important in the skin for maintaining normal keratinization, sebum production, hair growth cycle activity and bacterial flora.
  • Reductions in thyroid hormones lead to increased numbers of inactive (telogen) hair follicles, and causes disruption to the other normal features of the skin mentioned above.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers


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