Canis ISSN: 2398-2942

Skin: telogen defluxion

Synonym(s): Telogen effluvium

Contributor(s): David Scarff, Susan E Shaw

Introduction

  • Uncommon syndrome characterized by widespread hair loss.
  • Cause: stress → synchronization of anagen hair follicles into catagen.
  • Signs: shedding of large numbers of telogen hairs 1-3 months later.
  • Diagnosis: history, clinical signs, microscopy, histopathology.
  • Treatment: none.
  • Prognosis: excellent.

Pathogenesis

Etiology

  • Major physiological stress, eg pyrexia, pregnancy, lactation, surgery, anesthesia, shock, severe illness.

Predisposing factors

General
  • Major physiological stress.

Specific

  • Pyrexia.
  • Pregnancy.
  • Lactation.
  • Surgery.
  • Anesthesia.
  • Shock.
  • Severe illness.

Pathophysiology

  • Major metabolic stress → abrupt, premature cessation of growth of many anagen hair follicles → synchronization of these hair follicles in catagen → synchronization in telogen → new phase of follicular growth → shedding of large numbers of telogen hairs 1-3 months after stressful circumstance.

Timecourse

  • Days to weeks.

Diagnosis

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Outcomes

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Further Reading

Publications

Refereed papers

Other sources of information

  • Scott D W, Miller W H & Griffin C E (1995)Small Animal Dermatology.5th edn. Philadelphia: W B Saunders. ISBN 0 7216 4850 9.
  • Yager J A & Wilcock B P (1994)Color Atlas and Text of Surgical Pathology of the Dog and Cat.London: Wolfe Publishing, Mosby Year Book Europe. ISBN 0 7234 1827 6.
  • Gross T L, Irkhe P J & Walder E J (1992)Veterinary Dermatopathology.St Louis: Mosby Year Book. ISBN 0 8016 5809 8.
  • Fadok V A (1985)The dynamics of hair growth and development.Dermatol Rep4, 1.


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