Canis ISSN: 2398-2942

Skin: linear IgA syndrome

Synonym(s): linear IgA dermatosis

Contributor(s): David Scarff

Introduction

  • Cause: rare idiopathic dermatosis.
  • Only reported in adult Dachshund Dachshund.
  • Signs: skin lesions, pustules, alopecia, hyperpigmentation.
  • Diagnosis: history, clinical signs, histopathology.
  • Treatment: most cases respond to glucocorticoid therapy.
  • Prognosis: lifelong maintenance therapy required.

Pathogenesis

Pathophysiology

  • IgA deposition on basement membrane area → sub-corneal or intra-epidermal pustules which contain neutrophils but are sterile.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers


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