ISSN 2398-2969      

Skin: irritant contact dermatitis

icanis
Contributor(s):

David Scarff


Introduction

  • Dermatitis developing as a response to contact with irritant substance.
  • Distinguish from contact hypersensitivity Skin: allergic contact dermatitis which requires previous exposure to the agent.
  • Cause: skin inflammation due to direct contact with irritant.
  • Signs: localized pruritus.
  • Diagnosis: history, signs, histopathology.
  • Treatment: symptomatic and avoidance of source.
  • Prognosis: good.

Pathogenesis

Etiology

  • Reaction to irritant substance on skin:
    • Acid.
    • Alkali.
    • Shampoo.
    • Disinfectant.
    • Household or garden chemicals.
    • Flea collar.

Pathophysiology

  • Damage to the skin causes irritation.
  • Self-trauma with licking and scratching results in excoriation and pyotraumatic dermatitis.
  • Crusts, hyperpigmentation and eventually scarring may develop if treatment is inadequate.

Timecourse

  • Acute reaction over minutes to hours.

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

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