Canis ISSN: 2398-2942

Skin: intracutaneous cornifying epithelioma

Synonym(s): Keratoacanthoma, keratinizing acanthoma, infundibular keratinizing acanthoma

Contributor(s): David Godfrey, David Scarff, Susan E Shaw

Introduction

  • Likely hair follicle origin.
  • Cause: unknown but breed predispositions are recorded.
  • Signs: solitary or multiple keratin-filled cysts in dermis with demonstrable pore on surface.
  • Well delineated and benign.
  • Clinical problems due to mass effect, and with secondary inflammation after rupture.
  • Treatment: surgical resection, retinoids.
  • Diagnosis: presentation and histopathology.
  • Prognosis: good unless multiple.

Pathogenesis

Pathophysiology

  • Inflammation around the masses is seen if the neoplasm ruptures as a foreign body reaction occurs.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Henfrey J I (1991) Treatment of multiple intracutaneous cornifying epithelioma using isoretinoin. JSAP 32 (7), 363-365 VetMedResource.
  • Power H T & Ihrke P J (1990) Synthetic retinoids in veterinary dermatology. Vet Clin North Am 20 (6), 1525-39 PubMed.
  • Stannard A A & Pulley L T (1975) Intracutaneous cornifying epithelioma (keratoacanthoma) in the dog - a respective study of 25 cases. JAVMA 167 (5), 385-8 PubMed.

Other sources of information

  • Nuttall T, Harvey R G & McKeever P J (2009)A Colour Handbook of Skin diseases of the Dog and Cat.2nd edn. Manson Publishing, London. ISBN 978 1 84076 115 3.
  • Scott D W, Miller W H & Griffin C E (1995)Small Animal Dermatology.5th edn. Philadelphia: W B Saunders. ISBN 0 7216 4850 9.
  • Yager J A & Wilcock B P (1994)Color Atlas and Text of Surgical Pathology of the Dog and Cat.London: Wolfe Publishing, Mosby Year Book Europe. ISBN 0 7234 1827 6.
  • Goldschmidt M H & Schoffer F S (1992)Intracutaneous cornifying epithelioma.In:Skin Tumours of the Dog and Cat. Pergamon Press, New York. ISBN 080408230.
  • Gross T L, Irkhe P J & Walder E J (1992)Veterinary Dermatopathology.St Louis: Mosby Year Book. ISBN 0 8016 5809 8.


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