Canis ISSN: 2398-2942

Skin: hyperandrogenism

Contributor(s): Rosanna Marsella, David Scarff

Introduction

  • Cause: rarely documented syndrome; may be caused by testicular neoplasia or may be idiopathic.
  • Testicular neoplasia causes perianal gland and tail gland hyperplasia.
  • Signs: idiopathic hyperandrogenism causes truncal alopecia and greasy scaling.
  • Diagnosis: history, clinical signs, ultrasonography, hormone assay, response to castration.
  • Treatment: castration.
  • Prognosis: variable.

Pathogenesis

Etiology

  • Elevated serum androgen due to:

Pathophysiology

  • Increased serum androgen → excess stimulation of perianal (hepatoid) tissue of circumanal and tail gland as well as sebaceous glands → glandular hyperactivity → hyperplasia and increased secretion.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Scott E W & Reimers T J (1986) Tail gland and perianal gland hyperplasia associated with testicular neoplasia and hypertestosteronemia in a dog. Canine Practice 13 (1), 15-17 VetMedResource.

Other sources of information

  • Muller G Het al(ed) (1995)Small Animal Dermatology.5th edn. Philadelphia: W B Saunders, pp 678-679.


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